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Dihexa 10mg vial

Dihexa 10mg vial
$55.99

Dihexa is a synthetic peptide derived from angiotensin IV, designed to enhance cognitive function by promoting neurogenesis and synaptogenesis in the brain.

Overview

Dihexa, chemically known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide or PNB-0408, is a small peptide developed from angiotensin IV (Ang IV) to overcome its limitations, such as rapid degradation and poor blood-brain barrier penetration. It was designed to be brain-penetrant and stable, making it a promising candidate for cognitive enhancement and neuroprotection. 

 

Mechanism of Action

Dihexa primarily works by potentiating hepatocyte growth factor (HGF) signaling through its receptor c-Met, a key neurotrophic pathway in the central nervous system. This activation promotes: 

 
  • Neurogenesis: Growth of new neurons
  • Synaptogenesis: Formation and strengthening of synaptic connections
  • Neural plasticity: Enhanced communication between neurons, supporting learning and memory 
     

    Unlike traditional nootropics that modulate neurotransmitters, Dihexa enhances structural plasticity, effectively remodeling neural circuits to improve cognitive function. 
     
     

 

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